Background

Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.

Since 2004, Sygnature Discovery has delivered over 56 novel pre-clinical and 35 clinical compounds, with its scientists named on over 225 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, and more. To find out more, please visit www.sygnaturediscovery.com.

About the role

Bioscientists at Sygnature Discovery play essential roles in supporting and leading integrated client projects as well as developing and delivering customised biological screening assays to drive structure-activity relationships for preclinical drug discovery campaigns.

We are seeking bright Scientists who can help push the boundaries of our capabilities by contributing to the discovery of new drugs across a broad range of projects, molecular targets, and therapeutic indications. You should have recently completed a PhD in a relevant Biology-related discipline (e.g., Biochemistry, Enzymology, Biophysics, Cell Biology, Pharmacology) or have relevant industrial experience within a drug discovery environment.

Whether you are a Scientist looking to transition from academia to the pharmaceutical industry and jumpstart your career in drug discovery, or a Senior Scientist who has a good understanding in the application of drug discovery and is seeking broader exposure to biology, disease areas, screening platforms, and therapeutic modalities- we would love to hear from you!

Role Responsibilities:

• Designs and executes experiments independently.

• Identify and solve problems associated with own experiments and those of other team/project members as/if appropriate.

• Presents scientific findings, interpretations, and recommendations to the project/therapeutic/functional team, and/or clients with some guidance from the project leader or overseer.

• Support projects by developing good professional interpersonal relationships within the team supporting them to meet their project objectives and providing practical and scientific help and assistance to other team members as appropriate

• Propose and/or evaluate new opportunities in the areas of technology and process development.

• Develop an awareness of current developments in relevant scientific literature and shares these with other team/project members.

• Distinct project responsibilities relevant to project requirements e.g. ownership of slide collation, monitoring of reagent stocks.

• May attend and or recommend conferences aiming for a poster presentation, and present to external scientists and businesses.

• May take on leadership role with significant level of technical or scientific supervision/oversight within Bioscience only project supporting generation of project/therapeutic/functional required material.

Skills & Qualifications:

• Ideally you will be close to submission or have a PhD in Pharmacology, Biochemistry or a related Biology-specific discipline. Relevant industry experience within a drug discovery environment will also be considered.

• A strong scientific track record with experience built within a drug discovery environment is highly desirable.

• A working knowledge of current trends in drug discovery.

• Ability to develop novel assays from first principles and interpret complex biological datasets.

• Aptitude for proactive trouble-shooting and adoption of industry-leading practices for generation and analysis of robust scientific data.

• Experience of biochemical, biophysical or cellular technologies such as flow cytometry, RT-qPCR, high content imaging, Western Blotting, and SPR as applied to compound screening would be an advantage.

• Ability to work independently and as part of a larger team.

• Excellent written and verbal communication skills and an ability to present complex scientific ideas and datasets to key stakeholders.

Benefits

• 🌴 25 days annual leave (plus bank holidays)

• 🏥 Private Medical Insurance

• 🛡️ Life Insurance

• 🎯 Employee Assistance Programme

• ⚖️ Enhanced Family Friendly Policies

• 💰 Sygnature Group Pension Scheme

• 💚 1 paid volunteer day per year

Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.